Syntheses' of Analgesics. XXIII
نویسندگان
چکیده
منابع مشابه
ansa - Metallocene derivatives XXIII * .
9 Titanocene and zirconocene complexes with a phenyl or I-naphthyl substituent in one ,B-position of each Cs-ring ligand and with an interannular tetramethylethanoor dimethylsilano-bridge have been prepared. Racemic complex isomers, which are formed together with varying amounts of their meso isomers, were separated from the latter and characterised by lH NMR spectroscopy and X-ray crystallogra...
متن کاملXxiii. Oxidation-reduction Potentials of Pneumococcus
IN previous communications the electrode potential behaviour of haemolytic streptococci [Hewitt, 1930, 1], C. diphtheriae [1930, 2], staphylococci [1930, 3] and pneumococci [1930, 4] has been described by the author and it has been shown that the oxidation-reduction potentials established in bacterial cultures depend upon the cultural conditions and upon the organism studied. The potentials dev...
متن کاملOpioid Analgesics
Intensive research on the neurobiology of pain over the past two decades has revealed many receptors, ion channels and enzymes with potential as novel targets for development of a new generation of analgesic agents. However, despite large investment in preclinical and clinical development of small molecules and biologics as potential novel pain therapeutics, very few have reached the clinic. He...
متن کاملTopical analgesics.
BACKGROUND AND OBJECTIVES Pain treatment involves the usage of common and opioid analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs) and adjuvant analgesics. Traditionally, these drugs are administered systemically or into the neuraxis. However, when analgesics are applied through these pathways, they are associated with significant side effects, which can hinder its use. Topical administ...
متن کاملPharmacogenetics of new analgesics.
Patient phenotypes in pharmacological pain treatment varies between individuals, which could be partly assigned to their genotypes regarding the targets of classical analgesics (OPRM1, PTGS2) or associated signalling pathways (KCNJ6). Translational and genetic research have identified new targets, for which new analgesics are being developed. This addresses voltage-gated sodium, calcium and pot...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1959
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.79.8_1087